Potential Anticancer Activity of Tocotrienols

Pharmacological potential of tocotrienols: a review

Tocotrienols, members of the vitamin E family, are natural compounds found in a number of vegetable oils, wheat germ, barley, and certain types of nuts and grains. Like tocopherols, tocotrienols are also of four types viz. alpha, beta, gamma and delta. Unlike tocopherols, tocotrienols are unsaturated and possess an isoprenoid side chain. Tocopherols are lipophilic in nature and are found in ass...

Dose-dependent cholesterolemic activity of tocotrienols.

Tocotrienols and tocopherols are isoforms of vitamin E. Vitamin E may exhibit antioxidant, prooxidant and non-antioxidant activities depending upon circumstances. In this study, the effect of tocotrienols and a-tocopherol on the activities of HMG CoA reductase and cholesterol 7 a-hydroxylase was investigated. Pure tocotrienols were isolated from palm fatty acid distillate and pure a-tocopherol ...

Characterization of a Cell‐Penetrating Peptide with Potential Anticancer Activity

Cell-penetrating peptides (CPPs) are still an interesting and viable alternative for drug delivery applications. CPPs contain considerably high amounts of positively charged amino acids, imparting them with cationic character. Tumor cells are characterized by an enhanced anionic nature of their membrane surface, a property that could be used by CPPs to target these cells. We recently identified...

Anticancer Potential of Turmeric

Traditional Medicinal Use Turmeric powder has long been used for medicinal purposes in Asia to treat gastrointestinal upsets, arthritis pain, and "low energy." In traditional Indian Ayurvedic medicine, turmeric has been used as a tonic for the digestive system and the liver; to dispel worms, strengthen the body, and dissolve gallstones; and for menstrual irregularity and arthritis. In old Hindu...

Vitamin E: Tocotrienols The Science Behind Tocotrienols